E. coli engineered to become methanol addict to make
industry feedstocks. ChemistryWorld.com article.
A little biochem geeky stuff. Pull quote: “Lead author Julia Vorholt at ETH
Zurich says the first step was to get E. coli ‘addicted’ to methanol. ‘If you
make a mutation in a certain gene then [E. coli] needs to make a little bit of
biomass for some specific compounds from methanol,’ she explains. Leaving the
bacteria to grow in a bioreactor with just enough carbon to survive and an
abundance of methanol favours those that can use alcohol. Natural selection
takes over and bacteria which thrive using methanol outcompete the others until
eventually E. coli has evolved the same fixation cycle seen in other
methylotrophs.”
America’s crisis of repetition is hurting national
security. BreakingDefense.com article.
Pull quote: “Finally, the challenge of identifying obstacles to implementation
is hard — and frankly, not necessarily interesting. It involves detective work:
asking questions, knowing processes across government, and understanding
funding streams. It requires persistence and takes time. It’s a lot less
exciting than coming up with purportedly “new” ideas.”
Artemis Mission: Making NASA’s New Moon Suits.
Makezine.com article.
Pull quote: “This carefulness is evident when you walk into their sewing labs.
The labs are filled with single needle, double needle, off-arm, post, bar-tack,
serger, and zig-zag sewing machines, all used for the creation of the suits. In
typical clothing factories, the buzz of machines is constant and fast. Axiom’s
sewing lab is almost dead silent. Some of the sewers even turn the machines by
hand to achieve the level of precision needed.”
Agency Information Collection Activities: CISA Gateway
User Registration. Federal Register CISA 60-day
ICR renewal/change notice. Changes: “The collection was initially approved
on October 9, 2007, and the most recent approval was on December 19, 2023, with
an expiration date of June 30, 2024. The changes to the collection since the
previous OMB approval include; updating the title of the collection, decrease
in burden estimates and decrease in costs The total annual burden cost for this
collection has changed by $3,096.40, from $4,128 to $7,224.40 due to the
removal of the utilization survey, and the addition of PCIIMS respondents. For
the CISA Gateway, the total number of responses has increased from 350 to 700
due to the updated metrics resulting from the awareness campaign and due to the
registration process changing which does not include the training registration.
The annual government cost for this collection has changed by $8,340.92 from
$5,723 to $14,063.92 due to the removal of the utilization survey, and the
addition of PCIIMS respondents. The This is a renewal with changes of an
information collection.” Comments due June 24th, 2024.
National Security Telecommunications Advisory Committee.
Federal Register DHS meeting
notice. Agenda: “The NSTAC will meet in an open session on Thursday, May
23, 2024, from 3:15 p.m. to 4:30 p.m. EDT to discuss current NSTAC activities
and the government's ongoing cybersecurity and NS/EP communications
initiatives. This open session will include: (1) an update on the
administration's cybersecurity initiatives; (2) a keynote address;(3) an update
on current NSTAC activities; and (4) a status update on the NSTAC Principles
for Baseline Security Offerings from Cloud Service Providers Study.”
Sorry, Little Green Men: Alien Life Might Actually Be
Purple. ScientificAmerican.com article.
Pull quote: “Prior to that, microorganisms generated metabolic energy by
harnessing sunlight using a purple-pigmented molecule called retinal, whose
origin may have predated chlorophyll. If retinal exists on other faraway
worlds, scientists think the molecule's unique fingerprint would be discernible
by upcoming ground- and space-based telescopes.”
Monkeypox virus: dangerous strain gains ability to spread
through sex, new data suggest. Nature.com article. Pull quote:
“Although mpox infections have waned globally since 2022, they have been
trending upwards in the DRC: in 2023 alone, the country reported more than
14,600 suspected infections and more than 650 deaths. In September, 2023, a new
cluster of suspected cases arose in the DRC’s South Kivu province. This cluster
especially concerns researchers, as it has been spreading largely among sex
workers, suggesting that the virus has adapted to transmit readily through
sexual contact.
Remnants of bird flu virus found in pasteurized milk, FDA
says. OCRegister.com article.
Pull quote: “Because the detection of the bird flu virus known as Type A H5N1
in dairy cattle is new and the situation is evolving, no studies on the effects
of pasteurization on the virus have been completed, FDA officials said. But
past research shows that pasteurization is “very likely” to inactivate
heat-sensitive viruses like H5N1, the agency added.” While I agree with the
theory, I am not a big fan of ‘very likely’ as a scientific statement. And what
happens if A H5N1 fragments get into someone with an active flu infection;
would we see recombination?